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Support John Bull who ran in Sunday's London Marathon & PUMPA

Please support the Purine Laboratory at Guy's Hospital & PUMPA The Purine Metabolic Patients Association. The Laboratory Work relates to gene therapy, transplantation and anti cancer drugs, and it has put Britain in the forefront of the field, and remains the principal hope of Many suffers in all countries. Last Sunday's Marathon Runner John Bull has lost three sons all of whom died in Childhood from purine metabolic disease

To donate: Contact Dr Anne Simmonds at Guy's Hospital directly

Guys' London 00 71 955 4024

Or send a cheque to Purine Research Laboratory Guys Hospital London SE1 9RT made out to the Lab quoting Telegraph Onlineappeal.